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Prolonged cortisol exposure is associated with effects on the hippocampus and on memory

At clinical doses under supervision, the most common side effects are mild nausea in the first week (typically resolves by day 7 to 10), injection site reactions (redness, minor swelling, localized soreness lasting 24 hours), and occasional transient fatigue or mild headache in the first few days

This makes combination therapy particularly attractive in resistant cases or where long-term results are needed

What is the recommended frequency for monitoring Vitamin B12 levels in patients receiving intramuscular (IM) Vitamin B12 injections for replacement therapy?